The burden of coexistent allergic rhinitis and allergic conjunctivitis on health‑related quality of life

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Shuaib Kayode Aremu
AbdulAkeem Adebayo Aluko
Tayo Ibrahim

Abstract

Background: Allergic rhinitis (AR) is a symptom complex of consisting of nasal congestion, rhinorrhoea, sneezing and nasal itching arising from an IgE-mediated allergic reaction and inflammation of the mucosal lining of the nose and contiguous mucosal membranes usually due to airborne allergen. AR may occur inisolation or may coexist with allergic conjunctivitis (AC).


 Aim: The aim of this study is to assess and evaluate the importance of health-related quality of life (HR-QoL) in patients suffering from concomitant AC with AR with different types of quality-of-life instruments.


Methods: A sum of 220 patients who attended the outpatient department of ENT clinic were involved in this study. All patients undertook an ophthalmologic examination for coexistent AC. The rhino conjunctivitis quality of life questionnaire (RQLQ) was used to evaluate the quality of life in all patients.


Results: The mean age of the 220 patients(116 females and 104 males) involved in the study was 26.8 years. The male-to-female ratio was 1:1.1. Of the 220 patients, 55% studied up to secondary school graduation and 18% dwelt in the rural area. In the assessment of the statistics obtained from the AR and conjunctivitis symptom scoring, the mean total complaint score was found to be 13.2 ± 4.0.


Conclusion: AR can vary based on a region’s flora, weather and socioeconomic status. AR could lead to severe impairment in HR-QoL.

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How to Cite
The burden of coexistent allergic rhinitis and allergic conjunctivitis on health‑related quality of life. (2018). Port Harcourt Medical Journal, 12(3), 142-146. https://doi.org/10.60787/phmj.v12i3.103
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Original Articles

References

1. Ellwood PM. Shattuck lecture – Outcomes management. A technology of patient experience. N Engl J Med 1988;318:1549‑56.

2. Relman AS. Assessment and accountability: The third revolution in medical care. N Engl J Med 1988;319:1220‑2.

3. Wilson IB, Cleary PD. Linking clinical variables with health‑related quality of life. Aconceptual model of patient outcomes. JAMA 1995;273:59‑65.

4. Passàli D, Lauriello M, Bellussi L. Natural history of allergic rhinitis a review. Clin Appl Immunol Rev 2001;1:207‑16.

5. Asher MI, Keil U, Anderson HR, Beasley R, Crane J, Martinez F, et al. International study of asthma and allergies in childhood (ISAAC): Rationale and methods. Eur Respir J 1995;8:483‑91.

6. Özkırış M. Allergic rhinitis prevalence among 14‑17 years old students in Kayseri. Asthma Allergy Immunol 2010;8:163‑9.

7. Small M, Piercy J, Demoly P, Marsden H. Burden of illness and quality of life in patients being treated for seasonal allergic rhinitis: A cohort

survey. Clin Transl Allergy 2013;3:33.

8. Yazısız V, Yalçın AD, Afacan B, Avcı AB, Terzioğlu E. Evaluation of patients with allergic rhinitis in the province of Antalya. Asthma

Allergy Immunol 2007;5:61‑6.

9. Jacobs R, Martin B, Hampel F, Toler W, Ellsworth A, Philpot E. Effectiveness of fluticasone furoate 110 μg once daily in the treatment of nasal and ocular symptoms of seasonal allergic rhinitis in adults and adolescents sensitized to mountain cedar pollen. Curr Med Res Opin 2009; 25:1393‑401.

10. Bielory L. Allergic conjunctivitis and the impact of allergic rhinitis. Curr Allergy Asthma Rep 2010;10:122‑34.

11. DeWester J, Philpot EE, Westlund RE, Cook CK, Rickard KA. The efficacy of intranasal fluticasone propionate in the relief of ocular symptoms associated with seasonal allergic rhinitis. Allergy Asthma Proc 2003;24:331‑7.

12. Bartra J, MullolJ, MontoroJ, JaureguiI, Del CuvilloA, Davila I, et al. Effect of bilsatime upon the ocular symptoms of allergic rhinoconjunctivitis.

J Investig Allergol Clin Immunol 2011;21 Suppl 3:24‑33.

13. Lightman S, Scadding GK. Should intranasal corticosteroids be used for the treatment of ocular symptoms of allergic rhinoconjunctivitis?

A review of their efficacy and safety profile. Int Arch Allergy Immunol 2012;158:317‑25.

14. Hellings PW, Dobbels F, Denhaerynck K, Piessens M, Ceuppens JL, De Geest S, et al. Explorative study on patient’s perceived knowledge level, expectations, preferences and fear of side effects for treatment for allergic rhinitis. Clin Transl Allergy 2012;2:9.

15. Marple BF, Fornadley JA, Patel AA, Fineman SM, Fromer L, Krouse JH, et al. Keys to successful management of patients with allergic rhinitis: Focus on patient confidence, compliance, and satisfaction. Otolaryngol Head Neck Surg 2007;136:S107‑24.

16. Başak O, Başak S, Gültekin B, Tekin N, Söylemez A. The prevalence of allergic rhinitis in adults in Aydin, Turkey. Rhinology 2006;44:283‑7.

17. Cingi C, Cakli H, Us T, Akgün Y, Kezban M, Ozudogru E, et al. The prevalence of allergic rhinitis in urban and rural areas of Eskişehir‑Turkey. Allergol Immunopathol (Madr) 2005;33:151‑6.

18. Topal Ö, Erbek SS, Erbek S, Çakmak Ö. Epidemiological features, allergen distribution and symptom severity for the patients with perennial allergic rhinitis in Konya. J Ear Nose Throat 2008;18:227‑31.

19. Wüthrich B, Brignoli R, Canevascini M, Gerber M. Epidemiological survey in hay fever patients: Symptom prevalence and severity

and influence on patient management. Schweiz Med Wochenschr 1998;128:139‑43.

20. Nathan RA, Meltzer EO, Derebery J, Campbell UB, Stang PE, Corrao MA, et al. The prevalence of nasal symptoms attributed to allergies in the United States: Findings from the burden of rhinitis in an America survey. Allergy Asthma Proc 2008;29:600‑8.

21. Bonini S. Studies of allergic conjunctivitis. Chibret Int J 1987;5:12‑22.

22. Bousquet J, Van Cauwenberge P, Khaltaev N; Aria Workshop Group, World Health Organization. Allergic rhinitis and its impact on asthma.

J Allergy Clin Immunol 2001;108:S147‑334.

23. Strachan D, Sibbald B, Weiland S, Aït‑Khaled N, Anabwani G, Anderson HR, et al. Worldwide variations in prevalence of symptoms of allergic rhinoconjunctivitis in children: The International Study of Asthma and Allergies in Childhood (ISAAC). Pediatr Allergy Immunol 1997;8:161‑76.

24. Braun‑Fahrländer C, Wüthrich B, Gassner M, Grize L, Sennhauser FH, Varonier HS, et al. Validation of a rhinitis symptom questionnaire

(ISAAC core questions) in a population of swiss school children visiting the school health services. SCARPOL‑team. Swiss study on childhood allergy and respiratory symptom with respect to air pollution and climate. International Study of Asthma and Allergies in Childhood. Pediatr Allergy Immunol 1997;8:75‑82.

25. Rosario N, Bielory L. Epidemiology of allergic conjunctivitis. Curr Opin Allergy Clin Immunol 2011;11:471‑6.

26. Alrasyid H, McManus A, Mallon D, Nicholson C. Elevated body mass index is associated with severity of allergic rhinitis: Results from a cross

sectional study. Australas Med J 2008;2:56‑71.

27. Ono SJ, AbelsonMB. Allergic conjunctivitis: Update on pathophysiology and prospects for future treatment. J Allergy Clin Immunol

2005;115:118‑22.

28. Blaiss MS. Allergic rhinoconjunctivitis: Burden of disease. Allergy Asthma Proc 2007;28:393‑7.

29. Juniper EF, Guyatt GH, Dolovich J. Assessment of quality of life in adolescents with allergic rhinoconjunctivitis: Development and testing of a questionnaire for clinical trials. J Allergy Clin Immunol 1994;93:413‑23.

30. Thompson AK, Juniper E, Meltzer EO. Quality of life in patients with allergic rhinitis. Ann Allergy Asthma Immunol 2000;85:338‑47.